You should contact your GP or diabetes care team if: Urinary frequency significantly increases or becomes bothersome You experience pain, burning, or discomfort when urinating Urine appears cloudy, bloody, or has a strong odour You develop excessive thirst alongside increased urination You experience symptoms of dehydration (dizziness, dry mouth, dark urine) For urgent but non-emergency concerns, contact NHS 111 for advice
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If either exists, GLP-1 medications are absolutely contraindicated Medications reviewed: Ensure your medication timing plan accounts for levothyroxine separation Supplement review: Identify any supplements that might interact with either medication Starting dose strategy for thyroid patients Both semaglutide and tirzepatide are started at low doses and titrated upward
Maintain adequate hydration, ensure sufficient protein intake to preserve muscle mass, incorporate gentle physical activity, and consider simple analgesia such as paracetamol
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